Stardate 09.27.2026
London gave me a small lesson in Underground travel yesterday morning.
I left my hotel around 7:50 with my directions saved on my phone in case I lost internet. I thought I was doing everything right. The train was traveling in the correct direction, but Tower Hill wasn't a stop on that particular train.
So I got off and walked.
I still arrived on time.
That was the beginning of Day 1 at the DoNotAge conference.
During the social hour, I began seeing people I had met at last year's conference in New York City. One of the first familiar faces was Karen, a 77-year-old woman who looks decades younger than her age. We sat alongside Ryker, James and Jodie, who is new to DoNotAge. Our table was a good mix of Americans and Europeans.
It felt good to reunite with partners from last year.
Before the conference officially started, I talked with Paul Barradell, the CEO, about something that has been on my mind for some time.
Many of my doctor friends back home have questions about the products I've been taking for years. I understand the questions. These supplements aren't part of the traditional medical school curriculum, so there is naturally skepticism when new products enter the market.
One of my tennis partners is a doctor. He told me he receives NAD injections, which got me thinking more deeply about what I had been learning about NAD and its role in the body.
I discovered DoNotAge while researching my book, Live Long and Prosper. NMN was one of my first discoveries. It is a precursor involved in NAD production.
I came to this conference with questions.
I wanted to hear from experts and learn more about the research behind the products I've been taking.
The experts did not disappoint.
Vera Gorbanova, a pioneer in Sirt-6 research, was one of the first speakers. She opened with a question:
What causes aging?
She explained the role of Sirt-6 as an enzyme and discussed inflammation as a hallmark associated with age-related diseases. She also presented research showing greater Sirt-6 activity in longer-lived species.
Research involving mice was part of her presentation as well. She shared findings in which mice receiving Sirt-6 appeared younger and showed less frailty.
Sirt-6 happens to be one of the first products I added to my own supplement routine.
Her presentation set the tone for the rest of the day. Each speaker brought a different area of research to the room.
Company founder Alan Graves stood up and shared why he started DoNotAge. He became emotional when he told us his mother was sitting in the room with us.
He also shared that the company has now helped more than one million people pursue a healthier life.
Soren, from Denmark, talked about muscle mass reduction as we age. He shared research involving muscle recovery and spermidine, another product that has become part of my longevity routine.
During lunch, Soren stopped by our table and I had the opportunity to talk with him. Nicholás Cherñasly from Brazil joined the conversation. Nicholás shared a presentation about follow-up research he and his wife are doing related to a study that reported a 67 percent increase in longevity in mice.
Johnny and Lindsey gave a joint presentation about the new sachets. Their presentation generated quite a reaction in the room as they shared reports from patients experiencing changes in menopause symptoms. Some patients also reported better sleep and the elimination of dry mouth.
More research is needed.
That sentence stayed with me.
Research takes time. Questions lead to more questions. Conferences like this give researchers an opportunity to share what they are studying and give people like me an opportunity to listen.
I also had the opportunity to share my own work.
I brought signed copies of Live Long and Prosper with me and passed them out during the conference. Somehow, I managed to fit the books into my very small carry-on along with my small backpack.
My wife was surprised that everything I needed for a 12-day adventure through Scotland and London fit into those two bags.
The book that began with my own curiosity about longevity was now sitting in the hands of people working in the field that inspired it.
At the end of the day, I thanked Paul for a great first day and asked him for a picture together.
I came here with questions.
I left Day 1 with even more to learn.
“Let the favor of the Lord our God rest on us; establish the work of our hands for us— yes, establish the work of our hands.”
Psalm 90:17
Join me here:
https://substack.com/@michaelmulliganlivelong
A note about DoNotAge: DoNotAge is a partner of mine. If a reader chooses to purchase through my partner link, I receive a stipend. The discount code is LLAP, and the partner link can be found by clicking here. I encourage readers to do their own discovery and research.
Captain's Addendum
Spock: “Michael, your first London train experience appears to have provided useful data.”
Bones: “He got on the wrong train, Spock.”
Spock: “And still arrived on time. The data remains useful.”
I came here to learn. Today gave me plenty to think about, and tomorrow brings another full day with people who have devoted their lives to understanding how we age.
I'm grateful to be here.
And I'm grateful I brought the little book that started part of this journey with me.












